Therapeutic drugs?
Not all drugs are the same. There are many different substances that fall under the heading of drugs. Some fall under substance abuse, addictive substances or medicinal drugs such as marijuana. How drugs are used is of course the most important. Recently, hallucinogens and also psychedelics without hallucinogenic effects in particular have been in the spotlight when it comes to their therapeutic potential. We therefore consider the psychedelics to be a completely different sub-variant of the various types of drugs and psychedelics to be the least harmful. These are the least harmful and most researched; psilocybin from magic mushrooms and magic truffles. However, LSD and MDMA are also receiving increasing attention.
How do most psychedelics work therapeutically?
1: BDNF
The various psychedelics are almost all known to increase activity at the serotonin receptors. This is usually done because the psychedelics resemble serotonin and then fit into the same receptors. With some drugs such as MDMA, the activity is increased because more of the body's own stores of serotonin are released. As a whole, most effects are achieved through the stimulation of the serotonin receptor 5HT2a. The degree of stimulation of especially the 5HT2a receptor as well as a mix of other receptors causes a change in perception, mood and the creation of new connections in the brain. The new connections in the brain, in turn, is attributed to the additional production of the neurotrophin BDNF. When the body releases more BDNF, it flips the switch on a series of genes that grows brand new brain cells, nerve cells and number of connections. Even slightly higher BDNF makes you learn faster, remember better, age slower and your brain quickly rearranges connections to different parts of the brain and body.
BDNF also increases brain plasticity. When brain cells are damaged or put into a stressful situation, BDNF protects them and helps them come back stronger. Neural pathways become more flexible rather than broken down, which could explain why higher levels of BDNF are associated with warding off depression.
2: DMN activity
The Default Mode Network (DMN) includes brain regions in the cortex that are normally active during rest and is involved in event recall, social and emotional judgment, and future planning. Lowering the activity of the DMN causes time awareness to disappear and more living in the here and now. So that means worries and fears about the future disappear.
Thus, lower activity of the DMN results in lower stress levels and thus lower cortisol. Low cortisol allows the body to utilize its self-healing which allows it to fight disease and inflammation. Thanks to lowered inflammation levels, more serotonin is released, which in turn releases more BDNF, while also lowering anxiety and depression.
Read more about be in the now
3: Less ego
Psychedelics in higher doses cause self-awareness to slow down because a higher level of connectedness can be experienced. The ego usually wants to be fed more and more and often unhealthy things. The ego makes us restless and anxious since self-preservation is the ego's greatest goal. Without ego we will not survive but an overactive ego creates separation, loneliness and addictions.
Less ego means more connectedness, less depression, more serotonin, more BDNF, more healthy choices, less stress and less activity of the DMN.
4: Emotions are allowed to be there
It often happens that during a psilocybin session emotions come up that have been blocked for a long time. Releasing this "old pain" releases emotional blockages and sometimes psychosomatic complaints. It can sometimes feel like a liberation to uninhibitedly feel everything that needs to be felt. Because psychedelics can also give a feeling of satisfaction, the "negative" emotions can then often be felt more easily and processed into something one can be satisfied with.
5: Hallucinations
MDMA at normal doses gives almost no hallucinations while the other known psychedelics do. LSD, psilocybin and DMT (ayahuasca) are actually known to make you hallucinate. The hallucinations combined with the effects described above can provide new insights that can help, spiritual experiences or a very beautiful experience that cannot be explained in words. We believe it is also an insight into how the subconscious mind works and one can make healthier choices sooner with the new knowledge. Want to learn more about hallucinations? Then read on through the link:
Starting psychedelic therapy?
With us the trajectories start with the intake form. After filling out the intake, a first advice will be sent to you by mail with the advised trip and dosage. Furthermore, the mail will contain an explanation of what the approximate approach will be and how to make an appointment for the psychedelic session.
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